Refer: http://tipsonubuntu.com/2019/02/01/install-wine-4-0-ubuntu-18-10-16-04-14-04/
The official wine repository offers Ubuntu packages for all current Ubuntu releases, so you can easily install it via following steps:
1. Open terminal from application menu, then run command to enable 32 bit architecture:
sudo dpkg --add-architecture i386
Type user password (no visual feedback) when it prompts and hit Enter.
2. Run command to download and add the repository key:
wget -nc https://dl.winehq.org/wine-builds/winehq.key
sudo apt-key add winehq.key
3. For Ubuntu 18.04, Linux Mint 19.x, run command to add the repository:
sudo apt-add-repository 'deb https://dl.winehq.org/wine-builds/ubuntu/ bionic main'
For other releases, replace bionic in the code with:
cosmic for Ubuntu 18.10.
xenial for Ubuntu 16.04, and Linux Mint 18.x.
trusty for Ubuntu 14.04.
4. Finally check system package cache and install Wine 4.0:
sudo apt-get update
sudo apt-get install --install-recommends winehq-stable
For Ubuntu 18.04 and higher, you can skip apt-get update as it’s done after adding PPA.
How to Use Wine in Ubuntu:
Once installed, you need to generate configuration file by running command:
winecfg
It prompts you to install some libraries and finally launches the configuration dialog.
To run a .exe file, right-click on file, select “Open with Other Application”, and choose “Wine Windows Program Loader”.
Uninstall:
To remove Wine repository, go to Software & Updates -> Other Software, highlight the repository line and remove it.
Now you can install PlayOnLinux with the software store...